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Efficacy and Safety of a Microsomal Triglyceride Transfer Protein Inhibitor in Homozygous Familial Hypercholesterolemia

BACKGROUND: Patients with homozygous familial hypercholesterolemia (HoFH) respond inadequately to existing drugs. We conducted a phase 3 study to assess the efficacy and safety of the microsomal triglyceride transfer protein inhibitor lomitapide in adults with HoFH. METHODS: Twenty-nine subjects enr...

詳細記述

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書誌詳細
出版年:Lancet
主要な著者: Cuchel, M, Meagher, EA, du Toit, Theron H., Blom, DJ, Marais, AD, Hegele, RA, Averna, M, Sirtori, C, Shah, PK, Gaudet, D, Stefanutti, C, Vigna, GB, Du Plessis, AME, Propert, Kathleen J., Sasiela, WJ, Bloedon, LT, Rader, DJ
フォーマット: Artigo
言語:Inglês
出版事項: 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587657/
https://ncbi.nlm.nih.gov/pubmed/23122768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(12)61731-0
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