Efficacy and Safety of a Microsomal Triglyceride Transfer Protein Inhibitor in Homozygous Familial Hypercholesterolemia

BACKGROUND: Patients with homozygous familial hypercholesterolemia (HoFH) respond inadequately to existing drugs. We conducted a phase 3 study to assess the efficacy and safety of the microsomal triglyceride transfer protein inhibitor lomitapide in adults with HoFH. METHODS: Twenty-nine subjects enr...

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Detalhes bibliográficos
Publicado no:Lancet
Main Authors: Cuchel, M, Meagher, EA, du Toit, Theron H., Blom, DJ, Marais, AD, Hegele, RA, Averna, M, Sirtori, C, Shah, PK, Gaudet, D, Stefanutti, C, Vigna, GB, Du Plessis, AME, Propert, Kathleen J., Sasiela, WJ, Bloedon, LT, Rader, DJ
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587657/
https://ncbi.nlm.nih.gov/pubmed/23122768
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/S0140-6736(12)61731-0
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