SDHC methylation in gastrointestinal stromal tumors (GIST): a case report

BACKGROUND: Gastrointestinal stromal tumors (GIST) recently have been recognized as a genetically and biologically heterogeneous disease. In addition to KIT or PDGFRA mutated GIST, mutational inactivation of succinate dehydrogenase (SDH) subunits has been detected in the KIT/PDGFRA wild-type subgrou...

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Publicado en:BMC Med Genet
Autores principales: Urbini, Milena, Astolfi, Annalisa, Indio, Valentina, Heinrich, Michael C., Corless, Christopher L., Nannini, Margherita, Ravegnini, Gloria, Biasco, Guido, Pantaleo, Maria A.
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
Materias:
Case Report
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587653/
https://ncbi.nlm.nih.gov/pubmed/26415883
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12881-015-0233-7
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