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Endoplasmic reticulum and oxidant stress mediate nuclear factor-κB activation in the subfornical organ during angiotensin II hypertension

Endoplasmic reticulum (ER) stress and reactive oxygen species (ROS) generation in the brain circumventricular subfornical organ (SFO) mediate the central hypertensive actions of Angiotensin II (ANG II). However, the downstream signaling events remain unclear. Here we tested the hypothesis that angio...

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Veröffentlicht in:Am J Physiol Cell Physiol
Hauptverfasser: Young, Colin N., Li, Anfei, Dong, Frederick N., Horwath, Julie A., Clark, Catharine G., Davisson, Robin L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4587629/
https://ncbi.nlm.nih.gov/pubmed/25980014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00223.2014
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