Peroxynitrite Upregulates Angiogenic Factors VEGF-A, BFGF, and HIF-1α in Human Corneal Limbal Epithelial Cells

PURPOSE. Corneal neovascularization (NV) is a sight-threatening condition often associated with infection, inflammation, prolonged contact lens use, corneal burns, and acute corneal graft rejection. Macrophages recruited to the cornea release nitric oxide (NO) and superoxide anion (O(2)(−)), which r...

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Vydáno v:Invest Ophthalmol Vis Sci
Hlavní autoři: Ashki, Negin, Chan, Ann M., Qin, Yu, Wang, Wei, Kiyohara, Meagan, Lin, Lin, Braun, Jonathan, Wadehra, Madhuri, Gordon, Lynn K.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Association for Research in Vision and Ophthalmology 2014
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586970/
https://ncbi.nlm.nih.gov/pubmed/24398102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.13-12410
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