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Candida albicans adapts to host copper during infection by swapping metal cofactors for superoxide dismutase

Copper is both an essential nutrient and potentially toxic metal, and during infection the host can exploit Cu in the control of pathogen growth. Here we describe a clever adaptation to Cu taken by the human fungal pathogen Candida albicans. In laboratory cultures with abundant Cu, C. albicans expre...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Li, Cissy X., Gleason, Julie E., Zhang, Sean X., Bruno, Vincent M., Cormack, Brendan P., Culotta, Valeria Cizewski
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586888/
https://ncbi.nlm.nih.gov/pubmed/26351691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1513447112
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