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Candida albicans adapts to host copper during infection by swapping metal cofactors for superoxide dismutase

Copper is both an essential nutrient and potentially toxic metal, and during infection the host can exploit Cu in the control of pathogen growth. Here we describe a clever adaptation to Cu taken by the human fungal pathogen Candida albicans. In laboratory cultures with abundant Cu, C. albicans expre...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Li, Cissy X., Gleason, Julie E., Zhang, Sean X., Bruno, Vincent M., Cormack, Brendan P., Culotta, Valeria Cizewski
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586888/
https://ncbi.nlm.nih.gov/pubmed/26351691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1513447112
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