MINCR is a MYC-induced lncRNA able to modulate MYC’s transcriptional network in Burkitt lymphoma cells

Despite the established role of the transcription factor MYC in cancer, little is known about the impact of a new class of transcriptional regulators, the long noncoding RNAs (lncRNAs), on MYC ability to influence the cellular transcriptome. Here, we have intersected RNA-sequencing data from two MYC...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Doose, Gero, Haake, Andrea, Bernhart, Stephan H., López, Cristina, Duggimpudi, Sujitha, Wojciech, Franziska, Bergmann, Anke K., Borkhardt, Arndt, Burkhardt, Birgit, Claviez, Alexander, Dimitrova, Lora, Haas, Siegfried, Hoell, Jessica I., Hummel, Michael, Karsch, Dennis, Klapper, Wolfram, Kleo, Karsten, Kretzmer, Helene, Kreuz, Markus, Küppers, Ralf, Lawerenz, Chris, Lenze, Dido, Loeffler, Markus, Mantovani-Löffler, Luisa, Möller, Peter, Ott, German, Richter, Julia, Rohde, Marius, Rosenstiel, Philip, Rosenwald, Andreas, Schilhabel, Markus, Schneider, Markus, Scholz, Ingrid, Stilgenbauer, Stephan, Stunnenberg, Hendrik G., Szczepanowski, Monika, Trümper, Lorenz, Weniger, Marc A., Hoffmann, Steve, Siebert, Reiner, Iaccarino, Ingram
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2015
Matèries:
PNAS Plus
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586867/
https://ncbi.nlm.nih.gov/pubmed/26351698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1505753112
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