MINCR is a MYC-induced lncRNA able to modulate MYC’s transcriptional network in Burkitt lymphoma cells

Despite the established role of the transcription factor MYC in cancer, little is known about the impact of a new class of transcriptional regulators, the long noncoding RNAs (lncRNAs), on MYC ability to influence the cellular transcriptome. Here, we have intersected RNA-sequencing data from two MYC...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Doose, Gero, Haake, Andrea, Bernhart, Stephan H., López, Cristina, Duggimpudi, Sujitha, Wojciech, Franziska, Bergmann, Anke K., Borkhardt, Arndt, Burkhardt, Birgit, Claviez, Alexander, Dimitrova, Lora, Haas, Siegfried, Hoell, Jessica I., Hummel, Michael, Karsch, Dennis, Klapper, Wolfram, Kleo, Karsten, Kretzmer, Helene, Kreuz, Markus, Küppers, Ralf, Lawerenz, Chris, Lenze, Dido, Loeffler, Markus, Mantovani-Löffler, Luisa, Möller, Peter, Ott, German, Richter, Julia, Rohde, Marius, Rosenstiel, Philip, Rosenwald, Andreas, Schilhabel, Markus, Schneider, Markus, Scholz, Ingrid, Stilgenbauer, Stephan, Stunnenberg, Hendrik G., Szczepanowski, Monika, Trümper, Lorenz, Weniger, Marc A., Hoffmann, Steve, Siebert, Reiner, Iaccarino, Ingram
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2015
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PNAS Plus
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586867/
https://ncbi.nlm.nih.gov/pubmed/26351698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1505753112
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