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Not so Fast: Co-Requirements for Sonic Hedgehog Induced Brain Tumorigenesis
The Sonic hedgehog (Shh) pathway plays an integral role in cellular proliferation during normal brain development and also drives growth in a variety of cancers including brain cancer. Clinical trials of Shh pathway inhibitors for brain tumors have yielded disappointing results, indicating a more nu...
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| Publicado no: | Cancers (Basel) |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
MDPI
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4586781/ https://ncbi.nlm.nih.gov/pubmed/26258793 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers7030848 |
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