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Excess Secretion of Gel-Forming Mucins and Associated Innate Defense Proteins with Defective Mucin Un-Packaging Underpin Gallbladder Mucocele Formation in Dogs

Mucosal protection of the gallbladder is vital yet we know very little about the mechanisms involved. In domestic dogs, an emergent syndrome referred to as gallbladder mucocele formation is characterized by excessive secretion of abnormal mucus that results in obstruction and rupture of the gallblad...

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Publicat a:PLoS One
Autors principals: Kesimer, Mehmet, Cullen, John, Cao, Rui, Radicioni, Giorgia, Mathews, Kyle G., Seiler, Gabriela, Gookin, Jody L.
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586375/
https://ncbi.nlm.nih.gov/pubmed/26414376
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138988
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