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Error-prone repair of DNA double-strand breaks

Preserving the integrity of the DNA double helix is crucial for the maintenance of genomic stability. Therefore, DNA double-strand breaks represent a serious threat to cells. In this review, we describe the two major strategies used to repair double strand breaks: non-homologous end joining and homo...

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Détails bibliographiques
Publié dans:J Cell Physiol
Auteurs principaux: Rodgers, Kasey, McVey, Mitch
Format: Artigo
Langue:Inglês
Publié: 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586358/
https://ncbi.nlm.nih.gov/pubmed/26033759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcp.25053
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