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Highly Regioselective Indoline Synthesis under Nickel/Photoredox Dual Catalysis

Nickel/photoredox catalysis is used to synthesize indolines in one step from iodoacetanilides and alkenes. Very high regioselectivity for 3-substituted indoline products is obtained for both aliphatic and styrenyl olefins. Mechanistic investigations indicate that oxidation to Ni(III) is necessary to...

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Publicado en:J Am Chem Soc
Main Authors: Tasker, Sarah Z., Jamison, Timothy F.
Formato: Artigo
Idioma:Inglês
Publicado: 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586280/
https://ncbi.nlm.nih.gov/pubmed/26196355
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jacs.5b05597
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