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The past and the future of Alzheimer's disease CSF biomarkers—a journey toward validated biochemical tests covering the whole spectrum of molecular events

This paper gives a short review on cerebrospinal fluid (CSF) biomarkers for Alzheimer's disease (AD), from early developments to high-precision validated assays on fully automated lab analyzers. We also discuss developments on novel biomarkers, such as synaptic proteins and Aβ oligomers. Our vi...

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Detalhes bibliográficos
Publicado no:Front Neurosci
Main Authors: Blennow, Kaj, Zetterberg, Henrik
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586276/
https://ncbi.nlm.nih.gov/pubmed/26483625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnins.2015.00345
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