Bridging Tumor Genomics to Patient Outcomes through an Integrated Patient-Derived Xenograft (PDX) Platform

New approaches to optimizing cancer drug development in both the laboratory and the clinic will be required to fully achieve the goal of individualized, precision cancer therapy. Improved preclinical models that more closely reflect the now recognized genomic complexity of human cancers are needed....

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Pubblicato in:Clin Lung Cancer
Autori principali: Gandara, David R., Mack, Philip. C., Bult, Carol, Li, Tianhong, Lara, Primo N., Riess, Jonathan W., Astrow, Stephanie H., Gandour-Edwards, Regina, Cooke, David T., Yoneda, Ken Y., Moore, Elizabeth H., Pan, Chong-xian, Burich, Rebekah A., David, Elizabeth A., Keck, James G., Airhart, Susan, de Vere White, Ralph W., Liu, Edison T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4586173/
https://ncbi.nlm.nih.gov/pubmed/25838158
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cllc.2015.03.001
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