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The heptad repeat region is a major selection target in MERS-CoV and related coronaviruses

Middle East respiratory syndrome coronavirus (MERS-CoV) originated in bats and spread to humans via zoonotic transmission from camels. We analyzed the evolution of the spike (S) gene in betacoronaviruses (betaCoVs) isolated from different mammals, in bat coronavirus populations, as well as in MERS-C...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Forni, Diego, Filippi, Giulia, Cagliani, Rachele, De Gioia, Luca, Pozzoli, Uberto, Al-Daghri, Nasser, Clerici, Mario, Sironi, Manuela
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4585914/
https://ncbi.nlm.nih.gov/pubmed/26404138
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14480
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