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A mouse model replicating hippocampal sparing cranial irradiation in humans: A tool for identifying new strategies to limit neurocognitive decline

Cancer patients undergoing cranial irradiation are at risk of developing neurocognitive impairments. Recent evidence suggests that radiation-induced injury to the hippocampi could play an important role in this cognitive decline. As a tool for studying the mechanisms of hippocampal-dependent cogniti...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Tomé, Wolfgang A., Gökhan, Şölen, Brodin, N. Patrik, Gulinello, Maria E., Heard, John, Mehler, Mark F., Guha, Chandan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4585869/
https://ncbi.nlm.nih.gov/pubmed/26399509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14384
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