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Nanoparticle conjugation enhances the immunomodulatory effects of intranasally delivered CpG in house dust mite-allergic mice

An emerging strategy in preventing and treating airway allergy consists of modulating the immune response induced against allergens in the lungs. CpG oligodeoxynucleotides have been investigated in airway allergy studies, but even if promising, efficacy requires further substantiation. We investigat...

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Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Ballester, Marie, Jeanbart, Laura, de Titta, Alexandre, Nembrini, Chiara, Marsland, Benjamin J., Hubbell, Jeffrey A., Swartz, Melody A.
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4585708/
https://ncbi.nlm.nih.gov/pubmed/26387548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14274
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