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Nanoparticle conjugation enhances the immunomodulatory effects of intranasally delivered CpG in house dust mite-allergic mice

An emerging strategy in preventing and treating airway allergy consists of modulating the immune response induced against allergens in the lungs. CpG oligodeoxynucleotides have been investigated in airway allergy studies, but even if promising, efficacy requires further substantiation. We investigat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Ballester, Marie, Jeanbart, Laura, de Titta, Alexandre, Nembrini, Chiara, Marsland, Benjamin J., Hubbell, Jeffrey A., Swartz, Melody A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4585708/
https://ncbi.nlm.nih.gov/pubmed/26387548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14274
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