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Discovery of small molecule inhibitors of MyD88-dependent signaling pathways using a computational screen
In this study, we used high-throughput computational screening to discover drug-like inhibitors of the host MyD88 protein-protein signaling interaction implicated in the potentially lethal immune response associated with Staphylococcal enterotoxins. We built a protein-protein dimeric docking model o...
Enregistré dans:
| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4585646/ https://ncbi.nlm.nih.gov/pubmed/26381092 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep14246 |
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