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Autoantibodies to the GLUT-2 glucose transporter of beta cells in insulin-dependent diabetes mellitus of recent onset.

Purified immunoglobulin G (IgG) from the serum of patients with insulin-dependent diabetes mellitus (IDDM) of recent onset inhibits high-Km uptake of 3-O-methyl-beta-D-glucose by rat pancreatic islets. To determine if the inhibition is the result of antibodies against GLUT-2, the high-Km glucose tra...

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Publicado no:Proc Natl Acad Sci U S A
Principais autores: Inman, L R, McAllister, C T, Chen, L, Hughes, S, Newgard, C B, Kettman, J R, Unger, R H, Johnson, J H
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1993
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC45856/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8433987/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.90.4.1281
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