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Helicases in antiviral immunity: dual properties as sensors and effectors

Many helicases have a unique ability to couple cognate RNA binding to ATP hydrolysis, which can induce a large conformational change that affects its interaction with RNA, position along RNA, or oligomeric state. A growing number of these helicases contribute to the innate immune system, either as s...

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Detalhes bibliográficos
Publicado no:Trends Biochem Sci
Main Authors: Ahmad, Sadeem, Hur, Sun
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4584414/
https://ncbi.nlm.nih.gov/pubmed/26410598
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tibs.2015.08.001
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