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Heterogeneous DNA Methylation Patterns in the GSTP1 Promoter Lead to Discordant Results between Assay Technologies and Impede Its Implementation as Epigenetic Biomarkers in Breast Cancer

Altered DNA methylation patterns are found in many diseases, particularly in cancer, where the analysis of DNA methylation holds the promise to provide diagnostic, prognostic and predictive information of great clinical value. Methylation of the promoter-associated CpG island of GSTP1 occurs in many...

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Dettagli Bibliografici
Pubblicato in:Genes (Basel)
Autori principali: Grenaker Alnaes, Grethe I., Ronneberg, Jo Anders, Kristensen, Vessela N., Tost, Jörg
Natura: Artigo
Lingua:Inglês
Pubblicazione: MDPI 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4584334/
https://ncbi.nlm.nih.gov/pubmed/26393654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/genes6030878
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