Preventive Activity against Influenza (H1N1) Virus by Intranasally Delivered RNA-Hydrolyzing Antibody in Respiratory Epithelial Cells of Mice

The antiviral effect of a catalytic RNA-hydrolyzing antibody, 3D8 scFv, for intranasal administration against avian influenza virus (H1N1) was described. The recombinant 3D8 scFv protein prevented BALB/c mice against H1N1 influenza virus infection by degradation of the viral RNA genome through its i...

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Bibliografiske detaljer
Udgivet i:Viruses
Main Authors: Cho, Seungchan, Youn, Ha-Na, Hoang, Phuong Mai, Cho, Sungrae, Kim, Kee-Eun, Kil, Eui-Joon, Lee, Gunsup, Cho, Mun-Ju, Hong, Juhyun, Byun, Sung-June, Song, Chang-Seon, Lee, Sukchan
Format: Artigo
Sprog:Inglês
Udgivet: MDPI 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4584307/
https://ncbi.nlm.nih.gov/pubmed/26402693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v7092863
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