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Applying the ethoexperimental approach to neurodevelopmental syndrome research reveals exaggerated defensive behavior in Mecp2 mutant mice

Rett syndrome is a Pervasive Developmental Disorder (PDD) associated with de novo mutations of the methyl CpG-binding protein 2 (MECP2) gene. Mecp2 functions as a transcription factor that regulating the expression of hundreds of genes. Identification of the role of Mecp2 in specific neurodevelopmen...

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Detalhes bibliográficos
Publicado no:Physiol Behav
Main Authors: Pearson, Brandon L., Defensor, Erwin B., Blanchard, D. Caroline, Blanchard, Robert J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4584164/
https://ncbi.nlm.nih.gov/pubmed/26066729
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.physbeh.2015.03.035
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