Genetic variants of OCT1 influence glycemic response to metformin in Han Chinese patients with type-2 diabetes mellitus in Shanghai

Aims/hypothesis: Genetic variation in OCT1 can influence the glycemic response to metformin. We evaluated the effects of the OCT1 single-nucleotide polymorphisms (SNPs), rs1867351, rs4709400, rs628031, and rs2297374, on metformin efficacy in type-2 diabetes mellitus (DM) patients. Methods: We perfor...

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Publicat a:Int J Clin Exp Pathol
Autors principals: Zhou, Yong, Ye, Weiwei, Wang, Yi, Jiang, Zhikui, Meng, Xiangying, Xiao, Qian, Zhao, Qian, Yan, Jian
Format: Artigo
Idioma:Inglês
Publicat: e-Century Publishing Corporation 2015
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583948/
https://ncbi.nlm.nih.gov/pubmed/26464716
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