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Shikonin inhibits IFN-γ-induced K17 over-expression of HaCaT cells by interfering with STAT3 signaling

Objectives: We hypothesized that interferon-γ (IFN-γ) induces K17 over-expression in HaCaT cells by activating STAT3 and that Sh might inhibit the over-expression through interference of STAT3 signaling. Methods: In vitro culture of HaCaT cells treated with IFN-γ and measurement of K17 protein by en...

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Pathol
Main Authors: Liu, Lili, Wu, Yan, Cao, Kai, Xu, Yuan-Yuan, Gao, Xing-Hua, Chen, Hong-Duo, Geng, Long
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583899/
https://ncbi.nlm.nih.gov/pubmed/26464667
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