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Sequential gemcitabine and tamoxifen treatment enhances apoptosis and blocks transformation in bladder cancer cells

Bladder cancer is a common malignancy for which regional or metastatic disease is identified at diagnosis. The aim of this study was to determine whether tamoxifen (Tam), an estrogen receptor (ER) antagonist, can sensitize bladder cancer cell lines to gemcitabine (Gem) chemotherapy. ERα and ERβ prot...

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Detalhes bibliográficos
Publicado no:Oncol Rep
Main Authors: TAKEUCHI, HISASHI, MMEJE, CHINEDU O., JINESH, GOODWIN G., TAOKA, RIKIYA, KAMAT, ASHISH M.
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583834/
https://ncbi.nlm.nih.gov/pubmed/26323344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/or.2015.4220
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