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Escalation of i.v. cocaine intake in peri-adolescent vs. adult rats selectively bred for high (HiS) vs. low (LoS) saccharin intake

RATIONALE: Adolescence marks a period of increased vulnerability to the development of substance use disorders. High sweet preference is a genetically mediated behavioral trait that also predicts vulnerability to substances of abuse. Previous research has shown that while adolescent rats selectively...

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Bibliographic Details
Published in:Psychopharmacology (Berl)
Main Authors: Holtz, Nathan A., Carroll, Marilyn E.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583775/
https://ncbi.nlm.nih.gov/pubmed/23307070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-012-2958-8
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