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A High-resolution Imaging Approach to investigate Chromatin Architecture in Complex Tissues

We present ChromATin, a quantitative high-resolution imaging approach for investigating chromatin organization in complex tissues. This method combines analysis of epigenetic modifications by immunostaining, localization of specific DNA sequences by FISH, and high-resolution segregation of nuclear c...

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Bibliographic Details
Published in:Cell
Main Authors: Linhoff, Michael W., Garg, Saurabh K., Mandel, Gail
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583660/
https://ncbi.nlm.nih.gov/pubmed/26406379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.09.002
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