Spinal 5-HT(7) receptors induce phrenic motor facilitation via EPAC-mTORC1 signaling

Spinal serotonin type 7 (5-HT(7)) receptors elicit complex effects on motor activity. Whereas 5-HT(7) receptor activation gives rise to long-lasting phrenic motor facilitation (pMF), it also constrains 5-HT(2) receptor-induced pMF via “cross-talk inhibition.” We hypothesized that divergent cAMP-depe...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurophysiol
Prif Awduron: Fields, D. P., Springborn, S. R., Mitchell, G. S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2015
Pynciau:
Cellular and Molecular Properties of Neurons
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583563/
https://ncbi.nlm.nih.gov/pubmed/26269554
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/jn.00374.2015
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