Delivering HIV Gagp24 to DCIR Induces Strong Antibody Responses In Vivo

Targeting dendritic cell-specific endocytic receptors using monoclonal antibodies fused to desired antigens is an approach widely used in vaccine development to enhance the poor immunogenicity of protein-based vaccines and to induce immune responses. Here, we engineered an anti-human DCIR recombinan...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Flamar, Anne-Laure, Contreras, Vanessa, Zurawski, Sandra, Montes, Monica, Dereuddre-Bosquet, Nathatlie, Martinon, Frédéric, Banchereau, Jacques, Le Grand, Roger, Zurawski, Gerard, Levy, Yves
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583231/
https://ncbi.nlm.nih.gov/pubmed/26407317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135513
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