Systemic and Cardiac Depletion of M2 Macrophage through CSF-1R Signaling Inhibition Alters Cardiac Function Post Myocardial Infarction

The heart hosts tissue resident macrophages which are capable of modulating cardiac inflammation and function by multiple mechanisms. At present, the consequences of phenotypic diversity in macrophages in the heart are incompletely understood. The contribution of cardiac M2-polarized macrophages to...

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Bibliographic Details
Published in:PLoS One
Main Authors: Leblond, Anne-Laure, Klinkert, Kerstin, Martin, Kenneth, Turner, Elizebeth C., Kumar, Arun H., Browne, Tara, Caplice, Noel M.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583226/
https://ncbi.nlm.nih.gov/pubmed/26407006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137515
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