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Berardinelli-Seip congenital lipodystrophy 2 regulates adipocyte lipolysis, browning, and energy balance in adult animals

Mutations in BSCL2/SEIPIN cause Berardinelli-Seip congenital lipodystrophy type 2 (BSCL2), but the mechanisms whereby Bscl2 regulates adipose tissue function are unclear. Here, we generated adipose tissue (mature) Bscl2 knockout (Ad-mKO) mice, in which Bscl2 was specifically ablated in adipocytes of...

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Detalhes bibliográficos
Publicado no:J Lipid Res
Main Authors: Zhou, Hongyi, Lei, Xinnuo, Benson, Tyler, Mintz, James, Xu, Xiaojing, Harris, Ruth B., Weintraub, Neal L., Wang, Xiaoling, Chen, Weiqin
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Biochemistry and Molecular Biology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583079/
https://ncbi.nlm.nih.gov/pubmed/26269358
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M060244
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