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Sumoylation of the GTPase Ran by the RanBP2 SUMO E3 Ligase Complex

The SUMO E3 ligase complex RanBP2/RanGAP1*SUMO1/Ubc9 localizes at cytoplasmic nuclear pore complex (NPC) filaments and is a docking site in nucleocytoplasmic transport. RanBP2 has four Ran binding domains (RBDs), two of which flank RanBP2's E3 ligase region. We thus wondered whether the small G...

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Détails bibliographiques
Publié dans:J Biol Chem
Auteurs principaux: Sakin, Volkan, Richter, Sebastian M., Hsiao, He-Hsuan, Urlaub, Henning, Melchior, Frauke
Format: Artigo
Langue:Inglês
Publié: American Society for Biochemistry and Molecular Biology 2015
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4583052/
https://ncbi.nlm.nih.gov/pubmed/26251516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M115.660118
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