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Loss of the endothelial glycocalyx is associated with increased E-selectin mediated adhesion of lung tumour cells to the brain microvascular endothelium

BACKGROUND: Arrest of metastasising lung cancer cells to the brain microvasculature maybe mediated by interactions between ligands on circulating tumour cells and endothelial E-selectin adhesion molecules; a process likely to be regulated by the endothelial glycocalyx. Using human cerebral microvasc...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Rai, Srijana, Nejadhamzeeigilani, Zaynab, Gutowski, Nicholas J., Whatmore, Jacqueline L.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4582832/
https://ncbi.nlm.nih.gov/pubmed/26407999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-015-0223-9
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