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Binding partners of the kinase domains in Drosophila obscurin and their effect on the structure of the flight muscle

Drosophila obscurin (Unc-89) is a titin-like protein in the M-line of the muscle sarcomere. Obscurin has two kinase domains near the C-terminus, both of which are predicted to be inactive. We have identified proteins binding to the kinase domains. Kinase domain 1 bound Bällchen (Ball, an active kina...

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Publicat a:J Cell Sci
Autors principals: Katzemich, Anja, West, Ryan J. H., Fukuzawa, Atsushi, Sweeney, Sean T., Gautel, Mathias, Sparrow, John, Bullard, Belinda
Format: Artigo
Idioma:Inglês
Publicat: The Company of Biologists 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4582401/
https://ncbi.nlm.nih.gov/pubmed/26251439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.170639
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