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Refining multivariate disease phenotypes for high chip heritability

BACKGROUND: Statistical genetics shows that the success of both genetic association studies and genomic prediction methods is positively associated with the heritability of the trait used in the analysis. Identifying highly heritable components of a complex disease can thus enhance genetic studies o...

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Detalhes bibliográficos
Publicado no:BMC Med Genomics
Main Authors: Sun, Jiangwen, Kranzler, Henry R, Bi, Jinbo
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4582350/
https://ncbi.nlm.nih.gov/pubmed/26399736
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-8794-8-S3-S3
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