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Scaffold attachment factor B2 (SAFB2)-null mice reveal non-redundant functions of SAFB2 compared with its paralog, SAFB1

Scaffold attachment factors SAFB1 and SAFB2 are multifunctional proteins that share >70% sequence similarity. SAFB1-knockout (SAFB1(−/−)) mice display a high degree of lethality, severe growth retardation, and infertility in male mice. To assess the in vivo role of SAFB2, and to identify unique f...

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Bibliografski detalji
Izdano u:Dis Model Mech
Glavni autori: Jiang, Shiming, Katz, Tiffany A., Garee, Jason P., DeMayo, Francesco J., Lee, Adrian V., Oesterreich, Steffi
Format: Artigo
Jezik:Inglês
Izdano: The Company of Biologists 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4582101/
https://ncbi.nlm.nih.gov/pubmed/26092125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.019885
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