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Acute perioperative-stress-induced increase of atherosclerotic plaque volume and vulnerability to rupture in apolipoprotein-E-deficient mice is amenable to statin treatment and IL-6 inhibition

Myocardial infarction and stroke are frequent after surgical procedures and consume a considerable amount of benefit of surgical therapy. Perioperative stress, induced by surgery, is composed of hemodynamic and inflammatory reactions. The effects of perioperative stress on atherosclerotic plaques ar...

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Detalhes bibliográficos
Publicado no:Dis Model Mech
Main Authors: Janssen, Henrike, Wagner, Christian S., Demmer, Philipp, Callies, Simone, Sölter, Gesine, Loghmani-khouzani, Houra, Hu, Niandan, Schuett, Harald, Tietge, Uwe J. F., Warnecke, Gregor, Larmann, Jan, Theilmeier, Gregor
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4582096/
https://ncbi.nlm.nih.gov/pubmed/26092124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.018713
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