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Increased Expression of NAPDH Oxidase 4 (NOX4) in Systemic Sclerosis Dermal Fibroblasts: Regulation by Transforming Growth Factor β
OBJECTIVE: Systemic Sclerosis (SSc) is characterized by severe and often progressive skin and multiple internal organ fibrosis. The mechanisms responsible for these alterations remain obscure, although excessive ROS-mediated oxidative stress has been implicated. NOX4 is one of seven NADPH oxidase is...
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| Veröffentlicht in: | Arthritis Rheumatol |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4581953/ https://ncbi.nlm.nih.gov/pubmed/26096997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39242 |
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