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Allergen-induced Interleukin-18 promotes experimental eosinophilic esophagitis in mice

Elevated levels of IL-18 have been reported in a number of allergic diseases. We recently reported that IL-18 in the blood and IL-18Rα mRNA in the oesophagus are induced during human eosinophilic oesophagitis (EoE). Additionally, we earlier showed that iNKT cells are critical to EoE pathogenesis; ho...

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Detalhes bibliográficos
Publicado no:Immunol Cell Biol
Main Authors: Dutt, Parmesh, Shukla, Jai Shankar, Ventateshaiah, Sathisha Upparahalli, Mariswamy, Siddesha Jalahalli., Mattner, Jochen, Shukla, Anshi, Mishra, Anil
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581894/
https://ncbi.nlm.nih.gov/pubmed/25801352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/icb.2015.30
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