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Aurora B Regulates Formin mDia3 in Achieving Metaphase Chromosome Alignment
Proper bipolar attachment of sister kinetochores to the mitotic spindle is critical for accurate chromosome segregation in mitosis. Here we show an essential role of the formin mDia3 in achieving metaphase chromosome alignment. This function is independent of mDia3 actin nucleation activity, but is...
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| Publié dans: | Dev Cell |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2011
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4581877/ https://ncbi.nlm.nih.gov/pubmed/21397845 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2011.01.008 |
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