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Aurora B Regulates Formin mDia3 in Achieving Metaphase Chromosome Alignment

Proper bipolar attachment of sister kinetochores to the mitotic spindle is critical for accurate chromosome segregation in mitosis. Here we show an essential role of the formin mDia3 in achieving metaphase chromosome alignment. This function is independent of mDia3 actin nucleation activity, but is...

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Bibliografiske detaljer
Udgivet i:Dev Cell
Main Authors: Cheng, Lina, Zhang, Jiayin, Ahmad, Sana, Rozier, Lorene, Yu, Haiqian, Deng, Haiteng, Mao, Yinghui
Format: Artigo
Sprog:Inglês
Udgivet: 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581877/
https://ncbi.nlm.nih.gov/pubmed/21397845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.devcel.2011.01.008
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