Clusterin Seals the Ocular Surface Barrier in Mouse Dry Eye

Dry eye is a common disorder caused by inadequate hydration of the ocular surface that results in disruption of barrier function. The homeostatic protein clusterin (CLU) is prominent at fluid-tissue interfaces throughout the body. CLU levels are reduced at the ocular surface in human inflammatory di...

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Udgivet i:PLoS One
Main Authors: Bauskar, Aditi, Mack, Wendy J., Mauris, Jerome, Argüeso, Pablo, Heur, Martin, Nagel, Barbara A., Kolar, Grant R., Gleave, Martin E., Nakamura, Takahiro, Kinoshita, Shigeru, Moradian-Oldak, Janet, Panjwani, Noorjahan, Pflugfelder, Stephen C., Wilson, Mark R., Fini, M. Elizabeth, Jeong, Shinwu
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581869/
https://ncbi.nlm.nih.gov/pubmed/26402857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0138958
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