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Anticancer and apoptotic activities of oleanolic acid are mediated through cell cycle arrest and disruption of mitochondrial membrane potential in HepG2 human hepatocellular carcinoma cells

Hepatocellular carcinoma (HCC) is an aggressive form of cancer, with high rates of morbidity and mortality, a poor prognosis and limited therapeutic options. The objective of the present study was to demonstrate the anticancer activity of oleanolic acid in HepG2 human HCC cells. Cell viability was e...

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Pubblicato in:Mol Med Rep
Autori principali: ZHU, YUE-YONG, HUANG, HONG-YAN, WU, YIN-LIAN
Natura: Artigo
Lingua:Inglês
Pubblicazione: D.A. Spandidos 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581805/
https://ncbi.nlm.nih.gov/pubmed/26151733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2015.4033
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