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Lentiviral-mediated growth-associated protein-43 modification of bone marrow mesenchymal stem cells improves traumatic optic neuropathy in rats

The aim of the present study was to examine the effect of growth-associated protein-43 (GAP-43) on bone marrow mesenchymal stem cell (BMSC) differentiation in a rat model of traumatic optic neuropathy (TON). GAP-43 and short hairpin (sh)RNA-GAP-43 were inserted into pGLV5 and pGLV3 lentiviral vector...

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Publicat a:Mol Med Rep
Autors principals: ZHU, QI, LIU, ZAOXIA, WANG, CHENGUANG, NIE, LILI, HE, YUXI, ZHANG, YAN, LIU, XIN, SU, GUANFANG
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581804/
https://ncbi.nlm.nih.gov/pubmed/26238991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2015.4132
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