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Minocycline inhibits PARP-1 expression and decreases apoptosis in diabetic retinopathy

The present study aimed to investigate the mechanism underlying the effects of minocycline on diabetic retinopathy-associated cellular apoptosis. A total of 40 Sprague Dawley (SD) rats were used as a diabetic retinopathy model following injection with streptozotocin. Among the 34 rats in which the d...

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Publicat a:Mol Med Rep
Autors principals: WU, YING, CHEN, YONGDONG, WU, QIANG, JIA, LILI, DU, XINHUA
Format: Artigo
Idioma:Inglês
Publicat: D.A. Spandidos 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581760/
https://ncbi.nlm.nih.gov/pubmed/26165350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2015.4064
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