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Extract of Rhizoma Polygonum cuspidatum reduces early renal podocyte injury in streptozotocin-induced diabetic rats and its active compound emodin inhibits methylglyoxal-mediated glycation of proteins

Podocyte injury contributes to renal damage and, eventually, to the occurrence of proteinuria in diabetic nephropathy. The aim of the present study was to investigate the effect of an ethanol extract from Rhizoma Polygonum cuspidatum (P. cuspidatum) on proteinuria and podocyte injury, and elucidate...

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Detalhes bibliográficos
Publicado no:Mol Med Rep
Main Authors: SOHN, EUNJIN, KIM, JUNGHYUN, KIM, CHAN SIK, JO, KYUHYUNG, KIM, JIN SOOK
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581740/
https://ncbi.nlm.nih.gov/pubmed/26299942
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/mmr.2015.4214
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