Engrailed-2 (En2) deletion produces multiple neurodevelopmental defects in monoamine systems, forebrain structures and neurogenesis and behavior

Many genes involved in brain development have been associated with human neurodevelopmental disorders, but underlying pathophysiological mechanisms remain undefined. Human genetic and mouse behavioral analyses suggest that ENGRAILED-2 (EN2) contributes to neurodevelopmental disorders, especially aut...

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Detalhes bibliográficos
Publicado no:Hum Mol Genet
Main Authors: Genestine, Matthieu, Lin, Lulu, Durens, Madel, Yan, Yan, Jiang, Yiqin, Prem, Smrithi, Bailoor, Kunal, Kelly, Brian, Sonsalla, Patricia K., Matteson, Paul G., Silverman, Jill, Crawley, Jacqueline N., Millonig, James H., DiCicco-Bloom, Emanuel
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2015
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581606/
https://ncbi.nlm.nih.gov/pubmed/26220976
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddv301
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