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Efficient Estimation of Nonparametric Genetic Risk Function with Censored Data

With an increasing number of causal genes discovered for complex human disorders, it is crucial to assess the genetic risk of disease onset for individuals who are carriers of these causal mutations and compare the distribution of age-at-onset with that in non-carriers. In many genetic epidemiologic...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Biometrika
Hauptverfasser: WANG, YUANJIA, LIANG, BAOSHENG, TONG, XINGWEI, MARDER, KAREN, BRESSMAN, SUSAN, ORR-URTREGER, AVI, GILADI, NIR, ZENG, DONGLIN
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581539/
https://ncbi.nlm.nih.gov/pubmed/26412864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/biomet/asv030
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