Cannabinoid Receptor Type 2 (CB2) Dependent and Independent Effects of WIN55,212-2 on Atherosclerosis in Ldlr-null Mice

PURPOSE: WIN55,212-2, a potent synthetic agonist of cannabinoid receptor type 1 (CB1) and cannabinoid receptor type 2 (CB2), reduces atherosclerosis in apolipoprotein E (ApoE) null mice. Although pharmacologic evidence suggests the anti-atherosclerotic effects of WIN55,212-2 are mediated via CB2, th...

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Udgivet i:J Cardiol Ther
Main Authors: Netherland-Van Dyke, Courtney, Rodgers, Ward, Fulmer, Makenzie, Lahr, Zachary, Thewke, Douglas
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581537/
https://ncbi.nlm.nih.gov/pubmed/26413498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12970/2311-052X.2015.03.02.2
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