Use of eculizumab in crescentic IgA nephropathy: proof of principle and conundrum?

IgA nephropathy (IgAN) is characterized by a variable clinical course and multifaceted pathophysiology. There is substantial evidence to suggest that complement activation plays a pivotal role in the pathogenesis of the disease. Therefore, complement inhibition using the humanized anti-C5 monoclonal...

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Bibliografske podrobnosti
izdano v:Clin Kidney J
Main Authors: Ring, Troels, Pedersen, Birgitte Bang, Salkus, Giedrius, Goodship, Timothy H.J.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
Teme:
Contents
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581393/
https://ncbi.nlm.nih.gov/pubmed/26413271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ckj/sfv076
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