Pyrosequencing-Based Assays for Rapid Detection of HER2 and HER3 Mutations in Clinical Samples Uncover an E332E Mutation Affecting HER3 in Retroperitoneal Leiomyosarcoma

Mutations in Human Epidermal Growth Factor Receptors (HER) are associated with poor prognosis of several types of solid tumors. Although HER-mutation detection methods are currently available, such as Next-Generation Sequencing (NGS), alternative pyrosequencing allow the rapid characterization of sp...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: González-Alonso, Paula, Chamizo, Cristina, Moreno, Víctor, Madoz-Gúrpide, Juan, Carvajal, Nerea, Daoud, Lina, Zazo, Sandra, Martín-Aparicio, Ester, Cristóbal, Ion, Rincón, Raúl, García-Foncillas, Jesús, Rojo, Federico
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2015
Assuntos:
Communication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4581306/
https://ncbi.nlm.nih.gov/pubmed/26287187
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms160819447
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